L-Lysine increased the cytotoxicity effect of doxorubicin in MDA-MB-231 and MDA-MB-468 breast cancer cell lines
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Cell Kinetic Study of Tamoxifen Treated MCF-7 and MDA-MB 468 Breast Cancer Cell Lines
Apoptosis could be a major mechanism of antitumor effect of tamoxifen. Therefore this study is designed to characterize the kinetic behavior of tamoxifen-induced apoptosis in the estrogen receptor positive (ER+) and negative (ER-) cell lines, MCF-7 and MDA-MB-468. Frequency of cell death was examined by trypan blue and acridine orange staining. Annexin V-Fluorescein/PI was used in flow cytometr...
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Background & Aims: Triple-negative breast cancer cells refer to any breast cancer that does not express the genes for the estrogen, progesterone, and HER2 receptors. The Wnt signaling pathway is important in the development and progression of various types of cancers. Quinacrine, a derivative of 9-aminoacridine, has been shown to inhibit the growth of several types of cancer cells. In this stud...
متن کاملCytotoxicity of Euphorbia macroclada on MDA-MB-468 Breast Cancer Cell Line
It has been reported that different species of Euphorbia (Euphorbiaceae) have antitumor activity. Some reports also show that these plants have potential cytotoxic effect against different cell lines. In a program to screen the cytotoxicity of Iranian native plants, Euphorbia macroclada Boiss. was collected, identified, and the cytotoxic activity of dichloromethane, ethy...
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Linear, dimeric, tetrameric, and cyclic peptides derived from lactoferricin B, containing the RRWQWR motif, were designed, synthesized, purified, and characterized using RP-HPLC chromatography and MALDI-TOF mass spectrometry. The antibacterial activity of the designed peptides against E. coli (ATCC 11775 and 25922) and their cytotoxic effect against MDA-MB-468 and MDA-MB-231 breast cancer cell ...
متن کاملThe Cytotoxicity Effect of Extracted Pigment from Haloarcula sp. on MDA-MB-468 Breast Cancer Cell Line
Background: Halophilic microorganisms have the potential to produce new biomolecules, including anti-cancer compounds, for medical applications. The purpose of this study was to evaluate the anti-cancer properties of pigments extracted from native Iranian halophilic Archaeon. Materials and Methods: Pigment extract of Haloarcula sp. previously isolated and identified from Aran-Bidgol Lake was e...
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ژورنال
عنوان ژورنال: Annals of Oncology
سال: 2019
ISSN: 0923-7534
DOI: 10.1093/annonc/mdz343.042